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Solitary extramedullary plasmacytoma (EMP) is a rare tumor with a relatively low rate of progression to multiple myeloma as compared to solitary bone lesions. Diagnosis is based on immunomorphologic findings and correlation with ancillary radiographic and laboratory studies.
This is a case of a 54-year old male who initially presented with a gradually enlarging mass at the left pre-auricular area. The mass was surgically excised early in its course but recurred at its original site after a few months compelling a re-excision and total left parotidectomy. After a slide review and other ancillary procedures, diagnosis was established as a solitary extramedullary plasmacytoma. The patient was then advised adjuvant radiotherapy. However, even after a supposedly therapeutic surgical excision and aggressive adjuvant treatment, the tumor recurred to another remote site and subsequently progressed to multiple myeloma.